Blar i forfatter "Knutsen, Gunnar"
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Autologous chondrocyte implantation for hip osteochondritis functioning 15 years after operation
Johansen, Oddmund; Peterson, Lars; Avenarius, Derk; Knutsen, Gunnar (Journal article; Tidsskriftartikkel, 2016-11-30)<b>Background:</b> The autologous implantation technique (ACI) was first introduced in studies on cartilage defects in knees. It has later been used for the treatment of osteochondral knee lesions. The patient presented here had a hip osteochondral defect measuring 4 cm in diameter. He was a candidate for hip prosthesis because of serious pain and reduced function. Being young and highly motivated ... -
Cartilage Repair and Joint Preservation Medical and Surgical Treatment Options
Madry, Henning; Grün, Ulrich Wolfgang; Knutsen, Gunnar (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)Articular cartilage defects are most often caused by trauma and osteoarthritis and less commonly by metabolic disorders of the subchondral bone, such as osteonecrosis and osteochondritis dissecans. Such defects do not heal spontaneously in adults and can lead to secondary osteoarthritis. Medications are indicated for symptomatic relief. Slow-acting drugs in osteo - arthritis (SADOA), such as ... -
Collagen-covered autologous chondrocyte implantation versus autologous matrix-induced chondrogenesis: A randomized trial comparing 2 methods for repair of cartilage defects of the knee
Fossum, Vegard; Hansen, Ann Kristin; Wilsgaard, Tom; Knutsen, Gunnar (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-17)<i>Background</i>: Autologous matrix-induced chondrogenesis (AMIC) is a single-stage alternative to autologous chondrocyte implantation for treatment of localized cartilage defects of the knee. To our knowledge, no randomized controlled trial exists comparing the 2 methods.<p><p> <i>Purpose</i>: To evaluate any difference in the outcome of AMIC as compared with collagen-covered autologous chondrocyte ... -
Human endogenous retrovirus W Activity in cartilage of osteoarthritis patients
Bendiksen, Signy; Martinez, Inigo Zubiavrre; Tümmler, Conny; Knutsen, Gunnar; Elvenes, Jan; Olsen, Elisabeth; Olsen, Randi; Moens, Ugo (Journal article; Tidsskriftartikkel; Peer reviewed, 2014) -
In vitro chondrogenic potency of surplus chondrocytes from autologous transplantation procedures does not predict short-term clinical outcomes
Islam, Md Ashraful; Fossum, Vegard; Hansen, Ann Kristin; Urbarova, Ilona; Knutsen, Gunnar; Martinez, Inigo Zubiavrre (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-10)<p><i>Background</i>: Autologous chondrocyte implantation (ACI) has been used over the last two decades to treat focal cartilage lesions aiming to delay or prevent the onset of osteoarthritis; however, some patients do not respond adequately to the procedure. A number of biomarkers that can forecast the clinical potency of the cells have been proposed, but evidence for the relationship between in ... -
Quality of care for remote orthopaedic consultations using telemedicine: A randomised controlled trial
Buvik, Astrid Synnøve; Bugge, Einar; Knutsen, Gunnar; Småbrekke, Arvid; Wilsgaard, Tom (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-09-08)Background: Decentralised services using outreach clinics or modern technology are methods to reduce both patient transports and costs to the healthcare system. Telemedicine consultations via videoconference are one such modality. Before new technologies are implemented, it is important to investigate both the quality of care given and the economic impact from the use of this new technology. The aim ... -
The subchondral bone in articular cartilage repair : current problems in the surgical management
Gomoll, AH; Knutsen, Gunnar; Madry, H; van Dijk, N; Seil, R; Brittberg, M; Kon, E (Journal article; Tidsskriftartikkel; Peer reviewed, 2010)